6FKH

Chloroplast F1Fo conformation 2

6FKH の概要

• エントリーDOI: 10.2210/pdb6fkh/pdb
• EMDBエントリー: 4271
• 分子名称: ATP synthase subunit a, chloroplastic, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (12 entities in total)
• 機能のキーワード: atp synthase, membrane protein complex, molecular motor, membrane protein
• 由来する生物種: Spinacia oleracea (Spinach); 詳細
• タンパク質・核酸の鎖数: 26
• 化学式量合計: 597235.83

構造登録者

Hahn, A.,Vonck, J.,Mills, D.J.,Meier, T.,Kuehlbrandt, W. (登録日: 2018-01-24, 公開日: 2018-05-23, 最終更新日: 2024-10-23)

主引用文献

Hahn, A.,Vonck, J.,Mills, D.J.,Meier, T.,Kuhlbrandt, W.
Structure, mechanism, and regulation of the chloroplast ATP synthase.
Science, 360:-, 2018

PubMed Abstract: The chloroplast adenosine triphosphate (ATP) synthase uses the electrochemical proton gradient generated by photosynthesis to produce ATP, the energy currency of all cells. Protons conducted through the membrane-embedded F motor drive ATP synthesis in the F head by rotary catalysis. We determined the high-resolution structure of the complete cFF complex by cryo-electron microscopy, resolving side chains of all 26 protein subunits, the five nucleotides in the F head, and the proton pathway to and from the rotor ring. The flexible peripheral stalk redistributes differences in torsional energy across three unequal steps in the rotation cycle. Plant ATP synthase is autoinhibited by a β-hairpin redox switch in subunit γ that blocks rotation in the dark.

PubMed: 29748256
DOI: 10.1126/science.aat4318

実験手法

ELECTRON MICROSCOPY (4.2 Å)