6FK7

Crystal structure of N2C/D282C stabilized opsin bound to RS06

6FK7 の概要

• エントリーDOI: 10.2210/pdb6fk7/pdb
• 分子名称: Rhodopsin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... (6 entities in total)
• 機能のキーワード: rhodopsin, g protein-coupled receptors, retinitis pigmentosa, signaling protein, sensory transduction, photoreceptor protein, kintegral membrane protein, vision, membrane, receptor, transducer photoreceptor, small molecule complex, membrane protein
• 由来する生物種: Bos taurus (Bovine)
• 細胞内の位置: Membrane ; Multi- pass membrane protein : P02699
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42051.54

構造登録者

Mattle, D.,Standfuss, J.,Dawson, R. (登録日: 2018-01-23, 公開日: 2018-04-04, 最終更新日: 2024-01-17)

• 主引用文献: Mattle, D.,Kuhn, B.,Aebi, J.,Bedoucha, M.,Kekilli, D.,Grozinger, N.,Alker, A.,Rudolph, M.G.,Schmid, G.,Schertler, G.F.X.,Hennig, M.,Standfuss, J.,Dawson, R.J.P.; Ligand channel in pharmacologically stabilized rhodopsin.; Proc. Natl. Acad. Sci. U.S.A., 115:3640-3645, 2018; PubMed: 29555765; DOI: 10.1073/pnas.1718084115

実験手法

X-RAY DIFFRACTION (2.62 Å)