6FIV

STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR

Summary for 6FIV

Entry DOI	10.2210/pdb6fiv/pdb
Related PRD ID	PRD_000434
Descriptor	RETROPEPSIN, SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, ... (4 entities in total)
Functional Keywords	fiv protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Feline immunodeficiency virus
Total number of polymer chains	1
Total formula weight	13818.97
Authors	Li, M.,Lee, T.,Morris, G.,Laco, G.,Wong, C.,Olson, A.,Elder, J.,Wlodawer, A.,Gustchina, A. (deposition date: 1998-12-02, release date: 1998-12-09, Last modification date: 2023-12-27)
Primary citation	Li, M.,Morris, G.M.,Lee, T.,Laco, G.S.,Wong, C.H.,Olson, A.J.,Elder, J.H.,Wlodawer, A.,Gustchina, A. Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease Proteins, 38:29-40, 2000 Cited by PubMed: 10651036 DOI: 10.1002/(SICI)1097-0134(20000101)38:1<29::AID-PROT4>3.0.CO;2-N PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation