6FIV

STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR

6FIV の概要

• エントリーDOI: 10.2210/pdb6fiv/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000434
• 分子名称: RETROPEPSIN, SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, ... (4 entities in total)
• 機能のキーワード: fiv protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Feline immunodeficiency virus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13818.97

構造登録者

Li, M.,Lee, T.,Morris, G.,Laco, G.,Wong, C.,Olson, A.,Elder, J.,Wlodawer, A.,Gustchina, A. (登録日: 1998-12-02, 公開日: 1998-12-09, 最終更新日: 2023-12-27)

• 主引用文献: Li, M.,Morris, G.M.,Lee, T.,Laco, G.S.,Wong, C.H.,Olson, A.J.,Elder, J.H.,Wlodawer, A.,Gustchina, A.; Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease; Proteins, 38:29-40, 2000; PubMed: 10651036; DOI: 10.1002/(SICI)1097-0134(20000101)38:1<29::AID-PROT4>3.0.CO;2-N

実験手法

X-RAY DIFFRACTION (1.9 Å)