6FHU

Crystal structure of BAZ2A PHD zinc finger in complex with H3 3-mer peptide

Summary for 6FHU

• Entry DOI: 10.2210/pdb6fhu/pdb
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, ALA-ARG-TAM, ZINC ION, ... (6 entities in total)
• Functional Keywords: transcription, phd zinc finger, bromodomain, baz2a, histone, 3-mer, epigenetic h3
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus, nucleolus : Q9UIF9
• Total number of polymer chains: 7
• Total formula weight: 28330.27

Authors

Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-15, release date: 2018-03-21, Last modification date: 2018-05-02)

• Primary citation: Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A.; Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.; ACS Chem. Biol., 13:915-921, 2018; PubMed: 29529862; DOI: 10.1021/acschembio.7b01093

Experimental method

X-RAY DIFFRACTION (2 Å)