6FCU

The X-ray Structure of Lytic Transglycosylase Slt inactive mutant E503Q from Pseudomonas aeruginosa in complex with 4(NAG-NAMpentapeptide)

Summary for 6FCU

Entry DOI	10.2210/pdb6fcu/pdb
Descriptor	Soluble lytic murein transglycosylase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-3-O-[(2R)-1-amino-1-oxopropan-2-yl]-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ACETATE ION, ... (6 entities in total)
Functional Keywords	lytic transglycosylase, lyase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	72577.78
Authors	Batuecas, M.T.,Dominguez-Gil, T.,Hermoso, J.A. (deposition date: 2017-12-21, release date: 2018-04-18, Last modification date: 2024-01-17)
Primary citation	Lee, M.,Batuecas, M.T.,Tomoshige, S.,Dominguez-Gil, T.,Mahasenan, K.V.,Dik, D.A.,Hesek, D.,Millan, C.,Uson, I.,Lastochkin, E.,Hermoso, J.A.,Mobashery, S. Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt ofPseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A., 115:4393-4398, 2018 Cited by PubMed: 29632171 DOI: 10.1073/pnas.1801298115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation