6FCN

Crystal structure of human PCNA soaked with p47phox(106-127) peptide

Summary for 6FCN

Entry DOI	10.2210/pdb6fcn/pdb
Related	1AXC 6FCM
Descriptor	Proliferating cell nuclear antigen (2 entities in total)
Functional Keywords	proliferating cell nuclear antigen, nuclear protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	93294.87
Authors	Housset, D.,Frachet, P. (deposition date: 2017-12-20, release date: 2019-01-30, Last modification date: 2024-01-17)
Primary citation	Ohayon, D.,De Chiara, A.,Dang, P.M.,Thieblemont, N.,Chatfield, S.,Marzaioli, V.,Burgener, S.S.,Mocek, J.,Candalh, C.,Pintard, C.,Tacnet-Delorme, P.,Renault, G.,Lagoutte, I.,Favier, M.,Walker, F.,Hurtado-Nedelec, M.,Desplancq, D.,Weiss, E.,Benarafa, C.,Housset, D.,Marie, J.C.,Frachet, P.,El-Benna, J.,Witko-Sarsat, V. Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216:2669-2687, 2019 Cited by PubMed: 31492810 DOI: 10.1084/jem.20180371 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.22 Å)

Structure validation