6FC9

The 1,8-bis(aminomethyl)anthracene and Quadruplex-duplex junction complex

6FC9 の概要

• エントリーDOI: 10.2210/pdb6fc9/pdb
• NMR情報: BMRB: 34221
• 分子名称: DNA (27-MER), [8-(azaniumylmethyl)anthracen-1-yl]methylazanium (2 entities in total)
• 機能のキーワード: quadruplex, junction, non canonical dna strucute, ligand-dna complex, dna
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8683.73

構造登録者

Santana, A.,Serrano, I.,Montalvillo-Jimenez, L.,Corzana, F.,Bastida, A.,Jimenez-Barbero, J.,Gonzalez, C.,Asensio, J.L. (登録日: 2017-12-20, 公開日: 2019-04-10, 最終更新日: 2024-06-19)

• 主引用文献: Diaz-Casado, L.,Serrano-Chacon, I.,Montalvillo-Jimenez, L.,Corzana, F.,Bastida, A.,Santana, A.G.,Gonzalez, C.,Asensio, J.L.; De Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.; Chemistry, 2020; PubMed: 33368678; DOI: 10.1002/chem.202005026

実験手法

SOLUTION NMR