6F9V

Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with Sampatrilat.

6F9V の概要

• エントリーDOI: 10.2210/pdb6f9v/pdb
• 分子名称: Angiotensin-converting enzyme, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... (14 entities in total)
• 機能のキーワード: angiotensin-1 converting enzyme, ace inhibitor, sampatrilat, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 150517.73

構造登録者

Cozier, G.E.,Acharya, K.R. (登録日: 2017-12-15, 公開日: 2018-03-07, 最終更新日: 2024-01-17)

• 主引用文献: Cozier, G.E.,Schwager, S.L.,Sharma, R.K.,Chibale, K.,Sturrock, E.D.,Acharya, K.R.; Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.; FEBS J., 285:1477-1490, 2018; PubMed: 29476645; DOI: 10.1111/febs.14421

実験手法

X-RAY DIFFRACTION (1.69 Å)