6F9R

Crystal structure of human Angiotensin-1 converting enzyme N-domain in complex with Sampatrilat-Asp.

Summary for 6F9R

• Entry DOI: 10.2210/pdb6f9r/pdb
• Descriptor: Angiotensin-converting enzyme, TETRAETHYLENE GLYCOL, MAGNESIUM ION, ... (15 entities in total)
• Functional Keywords: angiotensin-1 converting enzyme, ace inhibitor, sampatrilat-asp, sampatrilat, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 151094.19

Authors

Cozier, G.E.,Acharya, K.R. (deposition date: 2017-12-15, release date: 2018-03-07, Last modification date: 2024-01-17)

• Primary citation: Cozier, G.E.,Schwager, S.L.,Sharma, R.K.,Chibale, K.,Sturrock, E.D.,Acharya, K.R.; Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity.; FEBS J., 285:1477-1490, 2018; PubMed: 29476645; DOI: 10.1111/febs.14421

Experimental method

X-RAY DIFFRACTION (1.85 Å)