6F97

Crystal structure of the V465T mutant of 5-(Hydroxymethyl)furfural Oxidase (HMFO)

6F97 の概要

• エントリーDOI: 10.2210/pdb6f97/pdb
• 分子名称: 5-(hydroxymethyl)furfural oxidase, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: sec-thiol oxidation, flavoprotein, alcohol oxidase, kinetic resolution, biocatalysis, enzyme engineering
• 由来する生物種: Methylovorus sp. (strain MP688)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115727.27

構造登録者

Pickl, M.,Swoboda, A.,Romero, E.,Winkler, C.K.,Binda, C.,Mattevi, A.,Faber, K.,Fraaije, M.W. (登録日: 2017-12-14, 公開日: 2018-02-14, 最終更新日: 2024-01-17)

• 主引用文献: Pickl, M.,Swoboda, A.,Romero, E.,Winkler, C.K.,Binda, C.,Mattevi, A.,Faber, K.,Fraaije, M.W.; Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase.; Angew. Chem. Int. Ed. Engl., 57:2864-2868, 2018; PubMed: 29384246; DOI: 10.1002/anie.201713189

実験手法

X-RAY DIFFRACTION (1.9 Å)