6F83

Crystal Structure of Human Galectin-1 in Complex With Thienyl-1,2, 3-triazolyl Thiodigalactoside Inhibitor

6F83 の概要

• エントリーDOI: 10.2210/pdb6f83/pdb
• 分子名称: Galectin-1, 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside (3 entities in total)
• 機能のキーワード: carbohydrate-recognition, beta sandwich, carbohydrate binding protein, sugar binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31209.55

構造登録者

Collins, P.M.,Blanchard, H. (登録日: 2017-12-12, 公開日: 2019-01-30, 最終更新日: 2024-01-17)

• 主引用文献: Peterson, A.,Collins, P.M.,Kahl-Knutsson, B.,Zetterberg, F.R.,Blanchard, H.,Leffler, H.,Nilsson, U.J.; Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands; To be published,

実験手法

X-RAY DIFFRACTION (2.2 Å)