6F7V

Crystal structure of LkcE E64Q mutant in complex with LC-KA05

Summary for 6F7V

• Entry DOI: 10.2210/pdb6f7v/pdb
• Related: 6F32
• Descriptor: LkcE, FLAVIN-ADENINE DINUCLEOTIDE, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: amine oxydase, cyclase, post-pks enzyme, tayloring enzyme, flavoprotein
• Biological source: Streptomyces rochei subsp. volubilis
• Total number of polymer chains: 2
• Total formula weight: 101427.30

Authors

Dorival, J.,Risser, F.,Jacob, C.,Collin, S.,Drager, G.,Kirschning, A.,Paris, C.,Chagot, B.,Gruez, A.,Weissman, K.J. (deposition date: 2017-12-12, release date: 2018-09-19, Last modification date: 2024-05-08)

• Primary citation: Dorival, J.,Risser, F.,Jacob, C.,Collin, S.,Drager, G.,Paris, C.,Chagot, B.,Kirschning, A.,Gruez, A.,Weissman, K.J.; Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis.; Nat Commun, 9:3998-3998, 2018; PubMed: 30266997; DOI: 10.1038/s41467-018-06323-w

Experimental method

X-RAY DIFFRACTION (3.03 Å)