6F5X

Crystal structure of the SYCP1 N-terminal head-to-head assembly in closed conformation

Summary for 6F5X

Entry DOI	10.2210/pdb6f5x/pdb
Descriptor	Synaptonemal complex protein 1, IODIDE ION, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	meiosis, chromosome structure, coiled-coil, self-assembly, structural protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	9572.55
Authors	Ratcliff, M.,Dunce, J.M.,Davies, O.R. (deposition date: 2017-12-04, release date: 2018-06-06, Last modification date: 2024-05-08)
Primary citation	Dunce, J.M.,Dunne, O.M.,Ratcliff, M.,Millan, C.,Madgwick, S.,Uson, I.,Davies, O.R. Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nat. Struct. Mol. Biol., 25:557-569, 2018 Cited by PubMed: 29915389 DOI: 10.1038/s41594-018-0078-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation