6F4X

Crystal structure of H. pylori purine nucleoside phosphorylase in complex with PO4 and formycin A

Summary for 6F4X

Entry DOI	10.2210/pdb6f4x/pdb
Related	5LU0 6F4W
Descriptor	Purine nucleoside phosphorylase DeoD-type, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	purine nucleoside phosphorylase, h. pylori, formycin a, hydrolase
Biological source	Helicobacter pylori (Campylobacter pylori)
Total number of polymer chains	6
Total formula weight	157541.80
Authors	Stefanic, Z. (deposition date: 2017-11-30, release date: 2018-02-14, Last modification date: 2018-04-25)
Primary citation	Narczyk, M.,Bertosa, B.,Papa, L.,Vukovic, V.,Lescic Asler, I.,Wielgus-Kutrowska, B.,Bzowska, A.,Luic, M.,Stefanic, Z. Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285:1305-1325, 2018 Cited by PubMed: 29430816 DOI: 10.1111/febs.14403 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.694 Å)

Structure validation