6F3J
The crystal structure of Glycogen Phosphorylase in complex with 10a
Summary for 6F3J
Entry DOI | 10.2210/pdb6f3j/pdb |
Descriptor | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, INOSINIC ACID, ... (5 entities in total) |
Functional Keywords | transferase |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98445.15 |
Authors | Kyriakis, E.,Stamati, E.C.V.,Stravodimos, G.A.,Skamnaki, V.T.,Leonidas, D.D. (deposition date: 2017-11-28, release date: 2018-02-28, Last modification date: 2024-05-01) |
Primary citation | Kun, S.,Begum, J.,Kyriakis, E.,Stamati, E.C.V.,Barkas, T.A.,Szennyes, E.,Bokor, E.,Szabo, K.E.,Stravodimos, G.A.,Sipos, A.,Docsa, T.,Gergely, P.,Moffatt, C.,Patraskaki, M.S.,Kokolaki, M.C.,Gkerdi, A.,Skamnaki, V.T.,Leonidas, D.D.,Somsak, L.,Hayes, J.M. A multidisciplinary study of 3-( beta-d-glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors. Eur J Med Chem, 147:266-278, 2018 Cited by PubMed: 29453094DOI: 10.1016/j.ejmech.2018.01.095 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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