6F2Q
Neutron crystal structure of perdeuterated galectin-3C in the ligand-free form
Summary for 6F2Q
| Entry DOI | 10.2210/pdb6f2q/pdb |
| Related | 6EXY 6EYM |
| Descriptor | Galectin-3 (2 entities in total) |
| Functional Keywords | galectin, hydrogen bonding, molecular recognition, perdeuteration, sugar binding protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 15701.05 |
| Authors | Manzoni, F.,Blakeley, M.P.,Oksanen, E.,Logan, D.T. (deposition date: 2017-11-27, release date: 2018-05-02, Last modification date: 2018-06-06) |
| Primary citation | Manzoni, F.,Wallerstein, J.,Schrader, T.E.,Ostermann, A.,Coates, L.,Akke, M.,Blakeley, M.P.,Oksanen, E.,Logan, D.T. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61:4412-4420, 2018 Cited by PubMed: 29672051DOI: 10.1021/acs.jmedchem.8b00081 PDB entries with the same primary citation |
| Experimental method | NEUTRON DIFFRACTION (1.757 Å) X-RAY DIFFRACTION (1.03 Å) |
Structure validation
Download full validation report
