6F1D

CUB2 domain of C1r

Summary for 6F1D

Entry DOI	10.2210/pdb6f1d/pdb
Descriptor	Complement C1r subcomponent, CALCIUM ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	cub domain, egf-like domain, complement, c1r-c1s, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Secreted : P00736
Total number of polymer chains	1
Total formula weight	13480.91
Authors	Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R. (deposition date: 2017-11-21, release date: 2018-01-17, Last modification date: 2024-01-17)
Primary citation	Almitairi, J.O.M.,Venkatraman Girija, U.,Furze, C.M.,Simpson-Gray, X.,Badakshi, F.,Marshall, J.E.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.E.,Wallis, R. Structure of the C1r-C1s interaction of the C1 complex of complement activation. Proc. Natl. Acad. Sci. U.S.A., 115:768-773, 2018 Cited by PubMed: 29311313 DOI: 10.1073/pnas.1718709115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation