6EZ2
Human butyrylcholinesterase carbamylated.
Summary for 6EZ2
| Entry DOI | 10.2210/pdb6ez2/pdb |
| Descriptor | Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | butyrylcholinesterase, rivastigmine analogues, alzheimer disease, central nervous system, inhibitor., hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 122640.50 |
| Authors | Brazzolotto, X.,de la Mora, E.,Dighe, S.N.,Ross, B.P. (deposition date: 2017-11-14, release date: 2018-12-12, Last modification date: 2024-02-07) |
| Primary citation | Dighe, S.N.,de la Mora, E.,Chan, S.,Kantham, S.,McColl, M.,Veliyath, S.K.,Miles, J.A.,Nessar, Z.,McGeary, R.P.,Silman, I.,Parat, M.O.,Weik, M.,Brazzolotto, X.,Ros, B.P. Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model. Commun Chem, 2019 Cited by DOI: 10.1038/s42004-019-0133-4PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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