6EZ2

Human butyrylcholinesterase carbamylated.

6EZ2 の概要

• エントリーDOI: 10.2210/pdb6ez2/pdb
• 分子名称: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: butyrylcholinesterase, rivastigmine analogues, alzheimer disease, central nervous system, inhibitor., hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 122640.50

構造登録者

Brazzolotto, X.,de la Mora, E.,Dighe, S.N.,Ross, B.P. (登録日: 2017-11-14, 公開日: 2018-12-12, 最終更新日: 2024-02-07)

• 主引用文献: Dighe, S.N.,de la Mora, E.,Chan, S.,Kantham, S.,McColl, M.,Veliyath, S.K.,Miles, J.A.,Nessar, Z.,McGeary, R.P.,Silman, I.,Parat, M.O.,Weik, M.,Brazzolotto, X.,Ros, B.P.; Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model.; Commun Chem, 2019; DOI: 10.1038/s42004-019-0133-4

実験手法

X-RAY DIFFRACTION (2.7 Å)