6EYM
Neutron crystal structure of perdeuterated galectin-3C in complex with lactose
Summary for 6EYM
| Entry DOI | 10.2210/pdb6eym/pdb |
| Related PRD ID | PRD_900004 |
| Descriptor | Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | galectin, hydrogen bonding, molecular recognition, perdeuteration, sugar binding protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 16043.35 |
| Authors | Manzoni, F.,Coates, L.,Blakeley, M.P.,Oksanen, E.,Logan, D.T. (deposition date: 2017-11-13, release date: 2018-09-12, Last modification date: 2020-07-29) |
| Primary citation | Manzoni, F.,Wallerstein, J.,Schrader, T.E.,Ostermann, A.,Coates, L.,Akke, M.,Blakeley, M.P.,Oksanen, E.,Logan, D.T. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61:4412-4420, 2018 Cited by PubMed: 29672051DOI: 10.1021/acs.jmedchem.8b00081 PDB entries with the same primary citation |
| Experimental method | NEUTRON DIFFRACTION (1.7 Å) X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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