6EYF

Butyrylcolinesterase expressed in CHO cells co-crystallised with a rivastigmine analogue

「6EUL」から置き換えられました

6EYF の概要

• エントリーDOI: 10.2210/pdb6eyf/pdb
• 分子名称: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose, [3-[(1~{R})-1-(dimethylamino)ethyl]-4-oxidanyl-phenyl] ~{N}-ethyl-~{N}-methyl-carbamate, ... (6 entities in total)
• 機能のキーワード: butyrylcholinesterase, alzheimer disease, organophosphate, carbamylated, rivastigmine analogue, rational design, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61113.92

構造登録者

Brazzolotto, X.,De la Mora, E.,Dighe, S.,Ross, B. (登録日: 2017-11-12, 公開日: 2018-11-21, 最終更新日: 2024-01-17)

• 主引用文献: Dighe, S.,De la Mora, E.,Chan, S.,Kantham, S.,McColl, G.,Veliyath, S.K.,Miles, J.A.,Nessar, Z.Y.,Mcgeary, R.,Silman, I.,Weik, I.,Parat, M.O.,Brazzolotto, X.,Ross, B.; Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model; Commun Chem, 2019; DOI: 10.1038/s42004-019-0133-4

実験手法

X-RAY DIFFRACTION (2.6 Å)