6EWZ

Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state

Summary for 6EWZ

Entry DOI	10.2210/pdb6ewz/pdb
Descriptor	GTP pyrophosphokinase, GUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total)
Functional Keywords	magic spot, (p)ppgpp, small alarmone synthetase, persistence, resistance, mrsa, staphylococcus, transferase
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	58349.50
Authors	Manav, M.C.,Brodersen, D.E. (deposition date: 2017-11-07, release date: 2018-01-24, Last modification date: 2024-01-17)
Primary citation	Manav, M.C.,Beljantseva, J.,Bojer, M.S.,Tenson, T.,Ingmer, H.,Hauryliuk, V.,Brodersen, D.E. Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP. J. Biol. Chem., 293:3254-3264, 2018 Cited by PubMed: 29326162 DOI: 10.1074/jbc.RA117.001374 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.24 Å)

Structure validation