6EWZ

Crystal structure of RelP (SAS2) from Staphylococcus aureus bound to AMPCPP and GTP in the pre-catalytic state

6EWZ の概要

• エントリーDOI: 10.2210/pdb6ewz/pdb
• 分子名称: GTP pyrophosphokinase, GUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (6 entities in total)
• 機能のキーワード: magic spot, (p)ppgpp, small alarmone synthetase, persistence, resistance, mrsa, staphylococcus, transferase
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58349.50

構造登録者

Manav, M.C.,Brodersen, D.E. (登録日: 2017-11-07, 公開日: 2018-01-24, 最終更新日: 2024-01-17)

• 主引用文献: Manav, M.C.,Beljantseva, J.,Bojer, M.S.,Tenson, T.,Ingmer, H.,Hauryliuk, V.,Brodersen, D.E.; Structural basis for (p)ppGpp synthesis by theStaphylococcus aureussmall alarmone synthetase RelP.; J. Biol. Chem., 293:3254-3264, 2018; PubMed: 29326162; DOI: 10.1074/jbc.RA117.001374

実験手法

X-RAY DIFFRACTION (2.24 Å)