6EWI
Oreochromis niloticus CEP120 second C2 domain (C2B) A200P + G307S mutant
Summary for 6EWI
Entry DOI | 10.2210/pdb6ewi/pdb |
Descriptor | Centrosomal protein 120 (2 entities in total) |
Functional Keywords | centriole centrosome basal body cilia, cytosolic protein |
Biological source | Oreochromis niloticus (Nile tilapia) |
Total number of polymer chains | 2 |
Total formula weight | 42101.98 |
Authors | van Breugel, M. (deposition date: 2017-11-04, release date: 2018-05-02, Last modification date: 2024-01-17) |
Primary citation | Joseph, N.,Al-Jassar, C.,Johnson, C.M.,Andreeva, A.,Barnabas, D.D.,Freund, S.M.V.,Gergely, F.,van Breugel, M. Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23:2805-2818, 2018 Cited by PubMed: 29847808DOI: 10.1016/j.celrep.2018.04.100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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