6EVM
Crystal structure of a Pro-9 complexed peptide-substrate-binding domain of human type II collagen prolyl 4-hydroxylase
Summary for 6EVM
Entry DOI | 10.2210/pdb6evm/pdb |
Related | 6EVL |
Descriptor | Prolyl 4-hydroxylase subunit alpha-2, Pro-9, SULFATE ION, ... (5 entities in total) |
Functional Keywords | tetratricopeptide repeat, collagen synthesis, prolyl 4-hydroxylase, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 12986.51 |
Authors | Murthy, A.V.,Sulu, R.,Koski, M.K.,Wierenga, R.K. (deposition date: 2017-11-02, release date: 2018-09-12, Last modification date: 2024-01-17) |
Primary citation | Murthy, A.V.,Sulu, R.,Koski, M.K.,Tu, H.,Anantharajan, J.,Sah-Teli, S.K.,Myllyharju, J.,Wierenga, R.K. Structural enzymology binding studies of the peptide-substrate-binding domain of human collagen prolyl 4-hydroxylase (type-II): High affinity peptides have a PxGP sequence motif. Protein Sci., 27:1692-1703, 2018 Cited by PubMed: 30168208DOI: 10.1002/pro.3450 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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