6ESS

Artificial imine reductase mutant S112A-N118P-K121A-S122M

Summary for 6ESS

Entry DOI	10.2210/pdb6ess/pdb
Descriptor	Streptavidin, {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III), IRIDIUM ION, ... (4 entities in total)
Functional Keywords	streptavidin, beta-barrel, biotin-binding protein
Biological source	Streptomyces avidinii
Cellular location	Secreted: P22629
Total number of polymer chains	1
Total formula weight	17907.18
Authors	Hestericova, M.,Heinisch, T.,Alonso-Cotchico, L.,Marechal, J.-D.,Vidossich, P.,Ward, T.R. (deposition date: 2017-10-24, release date: 2018-01-03, Last modification date: 2024-05-08)
Primary citation	Hestericova, M.,Heinisch, T.,Alonso-Cotchico, L.,Marechal, J.D.,Vidossich, P.,Ward, T.R. Directed Evolution of an Artificial Imine Reductase. Angew. Chem. Int. Ed. Engl., 57:1863-1868, 2018 Cited by PubMed: 29265726 DOI: 10.1002/anie.201711016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.91 Å)

Structure validation