6EQO

Tri-functional propionyl-CoA synthase of Erythrobacter sp. NAP1 with bound NADP+ and phosphomethylphosphonic acid adenylate ester

6EQO の概要

• エントリーDOI: 10.2210/pdb6eqo/pdb
• 分子名称: Acetyl-coenzyme A synthetase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: 3-hydroxpropionyl-coa synthetase, 3-hydroxpropionyl-coa dehydratase, acrylyl-coa reductase, central carbon metabolism, carbon dioxode fixation, 3-hydroxypropionate bi-cycle, natural fusion enzyme, substrate channeling, oxidoreductase
• 由来する生物種: Erythrobacter sp. NAP1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 403752.44

構造登録者

Zarzycki, J.,Bernhardsgruetter, I.,Voegeli, B.,Wagner, T.,Engilberge, S.,Girard, E.,Shima, S.,Erb, T.J. (登録日: 2017-10-13, 公開日: 2018-10-24, 最終更新日: 2018-11-28)

• 主引用文献: Bernhardsgrutter, I.,Vogeli, B.,Wagner, T.,Peter, D.M.,Cortina, N.S.,Kahnt, J.,Bange, G.,Engilberge, S.,Girard, E.,Riobe, F.,Maury, O.,Shima, S.,Zarzycki, J.,Erb, T.J.; The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite.; Nat. Chem. Biol., 14:1127-1132, 2018; PubMed: 30374166; DOI: 10.1038/s41589-018-0153-x

実験手法

X-RAY DIFFRACTION (2.7 Å)