6EPS
The ATAD2 bromodomain in complex with compound UZH-DQ41
Summary for 6EPS
Entry DOI | 10.2210/pdb6eps/pdb |
Descriptor | ATPase family AAA domain-containing protein 2, (2~{R})-~{N}-[5-[3,5-bis(oxidanyl)phenyl]-4-ethanoyl-1,3-thiazol-2-yl]piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | bromodomain, atad2, inhibitor, complex, cytosolic protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15911.98 |
Authors | Sledz, P.,Caflisch, A. (deposition date: 2017-10-12, release date: 2018-10-31, Last modification date: 2024-05-08) |
Primary citation | Sledz, P. Hitting a moving target: simulation and crystallography study of ATAD2 bromodomain blockers To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.081 Å) |
Structure validation
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