6EP4

Human butyrylcholinesterase in complex with decamethonium

Summary for 6EP4

Entry DOI	10.2210/pdb6ep4/pdb
Descriptor	Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DECAMETHONIUM ION, ... (7 entities in total)
Functional Keywords	complex, hydrolase, inhibitor, quaternary ammonium
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	62200.34
Authors	Nachon, F.,Brazzolotto, X.,Wandhammer, M.,Trovaslet-Leroy, M.,Rosenberry, T.L.,Macdonald, I.R.,Darvesh, S. (deposition date: 2017-10-10, release date: 2017-12-13, Last modification date: 2024-01-17)
Primary citation	Rosenberry, T.L.,Brazzolotto, X.,Macdonald, I.R.,Wandhammer, M.,Trovaslet-Leroy, M.,Darvesh, S.,Nachon, F. Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study. Molecules, 22:-, 2017 Cited by PubMed: 29186056 DOI: 10.3390/molecules22122098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.30005381157 Å)

Structure validation