6EP4

Human butyrylcholinesterase in complex with decamethonium

6EP4 の概要

• エントリーDOI: 10.2210/pdb6ep4/pdb
• 分子名称: Cholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, DECAMETHONIUM ION, ... (7 entities in total)
• 機能のキーワード: complex, hydrolase, inhibitor, quaternary ammonium
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62200.34

構造登録者

Nachon, F.,Brazzolotto, X.,Wandhammer, M.,Trovaslet-Leroy, M.,Rosenberry, T.L.,Macdonald, I.R.,Darvesh, S. (登録日: 2017-10-10, 公開日: 2017-12-13, 最終更新日: 2024-01-17)

• 主引用文献: Rosenberry, T.L.,Brazzolotto, X.,Macdonald, I.R.,Wandhammer, M.,Trovaslet-Leroy, M.,Darvesh, S.,Nachon, F.; Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.; Molecules, 22:-, 2017; PubMed: 29186056; DOI: 10.3390/molecules22122098

実験手法

X-RAY DIFFRACTION (2.30005381157 Å)