6EN3

Crystal structure of full length EndoS from Streptococcus pyogenes in complex with G2 oligosaccharide.

Summary for 6EN3

Entry DOI	10.2210/pdb6en3/pdb
Descriptor	Endo-beta-N-acetylglucosaminidase F2,Multifunctional-autoprocessing repeats-in-toxin, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
Functional Keywords	endoglycosidase/immunoglobulin/carbohydrate/endo-beta-n-acetylglucos aminidase, hydrolase
Biological source	Streptococcus pyogenes More
Total number of polymer chains	1
Total formula weight	134897.29
Authors	Trastoy, B.,Klontz, E.H.,Orwenyo, J.,Marina, A.,Wang, L.X.,Sundberg, E.J.,Guerin, M.E. (deposition date: 2017-10-04, release date: 2018-06-13, Last modification date: 2024-01-17)
Primary citation	Trastoy, B.,Klontz, E.,Orwenyo, J.,Marina, A.,Wang, L.X.,Sundberg, E.J.,Guerin, M.E. Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S. Nat Commun, 9:1874-1874, 2018 Cited by PubMed: 29760474 DOI: 10.1038/s41467-018-04300-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.903 Å)

Structure validation