6EMR
Solution structure of the LEDGF/p75 IBD - IWS1 (aa 446-548) complex
Summary for 6EMR
Entry DOI | 10.2210/pdb6emr/pdb |
NMR Information | BMRB: 34182 |
Descriptor | PC4 and SFRS1-interacting protein,Protein IWS1 homolog (1 entity in total) |
Functional Keywords | protein-protein complex, epigenetics, leukemia, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 23837.50 |
Authors | Veverka, V. (deposition date: 2017-10-03, release date: 2018-07-25, Last modification date: 2024-06-19) |
Primary citation | Sharma, S.,Cermakova, K.,De Rijck, J.,Demeulemeester, J.,Fabry, M.,El Ashkar, S.,Van Belle, S.,Lepsik, M.,Tesina, P.,Duchoslav, V.,Novak, P.,Hubalek, M.,Srb, P.,Christ, F.,Rezacova, P.,Hodges, H.C.,Debyser, Z.,Veverka, V. Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115:E7053-E7062, 2018 Cited by PubMed: 29997176DOI: 10.1073/pnas.1803909115 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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