6EFJ

Crystal structure of NDM-1 with compound 9

Summary for 6EFJ

Entry DOI	10.2210/pdb6efj/pdb
Descriptor	Metallo-beta-lactamase type 2, ZINC ION, (2R)-2-phenyl-2-(phenylamino)-N-(1H-tetrazol-5-yl)acetamide, ... (4 entities in total)
Functional Keywords	carbapenemase, tetrazole, inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	25027.81
Authors	Akhtar, A.,Chen, Y. (deposition date: 2018-08-16, release date: 2019-04-17, Last modification date: 2023-10-11)
Primary citation	Torelli, N.J.,Akhtar, A.,DeFrees, K.,Jaishankar, P.,Pemberton, O.A.,Zhang, X.,Johnson, C.,Renslo, A.R.,Chen, Y. Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5:1013-1021, 2019 Cited by PubMed: 30942078 DOI: 10.1021/acsinfecdis.9b00052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation