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6EEB

Calmodulin in complex with malbrancheamide

Summary for 6EEB
Entry DOI10.2210/pdb6eeb/pdb
DescriptorCalmodulin-1, (5aS,12aS,13aS)-8,9-dichloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, CALCIUM ION, ... (5 entities in total)
Functional Keywordsef hand, metal binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight17754.86
Authors
Beyett, T.S.,Fraley, A.E.,Tesmer, J.J.G. (deposition date: 2018-08-13, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citationBeyett, T.S.,Fraley, A.E.,Labudde, E.,Patra, D.,Coleman, R.C.,Eguchi, A.,Glukhova, A.,Chen, Q.,Williams, R.M.,Koch, W.J.,Sherman, D.H.,Tesmer, J.J.G.
Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
Proc.Natl.Acad.Sci.USA, 116:15895-15900, 2019
Cited by
PubMed: 31337679
DOI: 10.1073/pnas.1818547116
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.96 Å)
Structure validation

222926

數據於2024-07-24公開中

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