6EDU
B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195
Summary for 6EDU
Entry DOI | 10.2210/pdb6edu/pdb |
EMDB information | 7516 9038 |
Descriptor | Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | hiv-1 env, broadly neutralizing antibodies, cryo-em, single particle analysis, viral protein-immune system complex, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 21 |
Total formula weight | 601818.34 |
Authors | Barnes, C.O.,Bjorkman, P.J. (deposition date: 2018-08-11, release date: 2018-10-17, Last modification date: 2020-07-29) |
Primary citation | Wang, H.,Barnes, C.O.,Yang, Z.,Nussenzweig, M.C.,Bjorkman, P.J. Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion. Cell Host Microbe, 24:579-592.e4, 2018 Cited by PubMed: 30308160DOI: 10.1016/j.chom.2018.09.003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.06 Å) |
Structure validation
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