6EC8

Glutamylation domain, TbtB, from thiomuracin biosynthesis bound to 5'-phosphodesmethylglutamycin

Summary for 6EC8

Entry DOI	10.2210/pdb6ec8/pdb
Descriptor	Lantibiotic dehydratase domain protein, 3'-deoxy-3'-[(L-alpha-glutamyl)amino]adenosine 5'-(dihydrogen phosphate) (3 entities in total)
Functional Keywords	ripp, thiopeptide, thiomuracin, trna-dependent, glutamylation, dehydratase, biosynthetic protein
Biological source	Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
Total number of polymer chains	1
Total formula weight	96482.19
Authors	Cogan, D.P.,Nair, S.K. (deposition date: 2018-08-07, release date: 2019-06-19, Last modification date: 2023-10-11)
Primary citation	Bothwell, I.R.,Cogan, D.P.,Kim, T.,Reinhardt, C.J.,van der Donk, W.A.,Nair, S.K. Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics. Proc.Natl.Acad.Sci.USA, 116:17245-17250, 2019 Cited by PubMed: 31409709 DOI: 10.1073/pnas.1905240116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.148 Å)

Structure validation