6EC8

Glutamylation domain, TbtB, from thiomuracin biosynthesis bound to 5'-phosphodesmethylglutamycin

6EC8 の概要

• エントリーDOI: 10.2210/pdb6ec8/pdb
• 分子名称: Lantibiotic dehydratase domain protein, 3'-deoxy-3'-[(L-alpha-glutamyl)amino]adenosine 5'-(dihydrogen phosphate) (3 entities in total)
• 機能のキーワード: ripp, thiopeptide, thiomuracin, trna-dependent, glutamylation, dehydratase, biosynthetic protein
• 由来する生物種: Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 96482.19

構造登録者

Cogan, D.P.,Nair, S.K. (登録日: 2018-08-07, 公開日: 2019-06-19, 最終更新日: 2023-10-11)

• 主引用文献: Bothwell, I.R.,Cogan, D.P.,Kim, T.,Reinhardt, C.J.,van der Donk, W.A.,Nair, S.K.; Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.; Proc.Natl.Acad.Sci.USA, 116:17245-17250, 2019; PubMed: 31409709; DOI: 10.1073/pnas.1905240116

実験手法

X-RAY DIFFRACTION (2.148 Å)