6EC3

Crystal Structure of EvdMO1

Summary for 6EC3

Entry DOI	10.2210/pdb6ec3/pdb
Related	5T38 5T39
Descriptor	Methyltransferase domain-containing protein, NICKEL (II) ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
Functional Keywords	methyltransferase, rossmann-like fold, sam-dependent, nonheme iron akg-dependent oxygenase, transferase, oxidoreductase
Biological source	Micromonospora carbonacea
Total number of polymer chains	3
Total formula weight	157089.96
Authors	McCulloch, K.M.,Iverson, T.M.,Starbird, C.A.,Perry, N.A.,Chen, Q.,Berndt, S.,Yamakawa, I.,Loukachevitch, L.V. (deposition date: 2018-08-07, release date: 2018-12-26, Last modification date: 2023-10-11)
Primary citation	Starbird, C.A.,Perry, N.A.,Chen, Q.,Berndt, S.,Yamakawa, I.,Loukachevitch, L.V.,Limbrick, E.M.,Bachmann, B.O.,Iverson, T.M.,McCulloch, K.M. The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains. Biochemistry, 57:6827-6837, 2018 Cited by PubMed: 30525509 DOI: 10.1021/acs.biochem.8b00836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.35 Å)

Structure validation