6EC3

Crystal Structure of EvdMO1

6EC3 の概要

• エントリーDOI: 10.2210/pdb6ec3/pdb
• 関連するPDBエントリー: 5T38 5T39
• 分子名称: Methyltransferase domain-containing protein, NICKEL (II) ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• 機能のキーワード: methyltransferase, rossmann-like fold, sam-dependent, nonheme iron akg-dependent oxygenase, transferase, oxidoreductase
• 由来する生物種: Micromonospora carbonacea
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 157089.96

構造登録者

McCulloch, K.M.,Iverson, T.M.,Starbird, C.A.,Perry, N.A.,Chen, Q.,Berndt, S.,Yamakawa, I.,Loukachevitch, L.V. (登録日: 2018-08-07, 公開日: 2018-12-26, 最終更新日: 2023-10-11)

• 主引用文献: Starbird, C.A.,Perry, N.A.,Chen, Q.,Berndt, S.,Yamakawa, I.,Loukachevitch, L.V.,Limbrick, E.M.,Bachmann, B.O.,Iverson, T.M.,McCulloch, K.M.; The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.; Biochemistry, 57:6827-6837, 2018; PubMed: 30525509; DOI: 10.1021/acs.biochem.8b00836

実験手法

X-RAY DIFFRACTION (3.35 Å)