6EBP

Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form

6EBP の概要

• エントリーDOI: 10.2210/pdb6ebp/pdb
• 分子名称: Ribonucleoside-diphosphate reductase, beta subunit, CALCIUM ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: ribonucleotide reductase, beta subunit, rnr, r2, class ie, metal-free, post-translational modification, ptm, dopa, radical, oxidoreductase
• 由来する生物種: Aerococcus urinae (strain ACS-120-V-Col10a)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 163338.38

構造登録者

Palowitch, G.M.,Boal, A.K. (登録日: 2018-08-06, 公開日: 2018-09-19, 最終更新日: 2023-10-11)

• 主引用文献: Blaesi, E.J.,Palowitch, G.M.,Hu, K.,Kim, A.J.,Rose, H.R.,Alapati, R.,Lougee, M.G.,Kim, H.J.,Taguchi, A.T.,Tan, K.O.,Laremore, T.N.,Griffin, R.G.,Krebs, C.,Matthews, M.L.,Silakov, A.,Bollinger Jr., J.M.,Allen, B.D.,Boal, A.K.; Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.; Proc. Natl. Acad. Sci. U.S.A., 115:10022-10027, 2018; PubMed: 30224458; DOI: 10.1073/pnas.1811993115

実験手法

X-RAY DIFFRACTION (1.59 Å)