6EAK

CRYSTAL STRUCTURE OF FUSION INHIBITOR JNJ-2408068 IN COMPLEX WITH HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN ESCAPE VARIANT T400A STABILIZED IN THE PREFUSION STATE

6EAK の概要

• エントリーDOI: 10.2210/pdb6eak/pdb
• 分子名称: Fusion glycoprotein F0, SULFATE ION, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (6 entities in total)
• 機能のキーワード: class i viral fusion protein, fusion, respiratory syncytial virus, prefusion, viral protein, fusion inhibitor
• 由来する生物種: Human respiratory syncytial virus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 64425.19

構造登録者

Battles, M.B.,McLellan, J.S. (登録日: 2018-08-03, 公開日: 2019-08-07, 最終更新日: 2024-10-09)

• 主引用文献: Battles, M.B.,McLellan, J.S.; Structural Basis for Respiratory Syncytial Virus Fusion Inhibitor Resistance; To be published,

実験手法

X-RAY DIFFRACTION (2.6 Å)