6E97

Crystal structure of the aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with DHB-adenylate

Summary for 6E97

• Entry DOI: 10.2210/pdb6e97/pdb
• Descriptor: 2,3-dihydroxybenzoate-AMP ligase, 5'-O-[(S)-[(2,3-dihydroxybenzene-1-carbonyl)oxy](hydroxy)phosphoryl]adenosine, SULFATE ION, ... (5 entities in total)
• Functional Keywords: siderophore biosynthesis, adenylation domain, dihydroxybenzoic acid activating enzyme, ligase
• Biological source: Thermobifida fusca
• Total number of polymer chains: 2
• Total formula weight: 120647.63

Authors

Bruner, S.D.,Zagulyaeva, A.A. (deposition date: 2018-07-31, release date: 2019-08-21, Last modification date: 2023-10-11)

• Primary citation: Bruner, S.D.,Zagulyaeva, A.A.; Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)