6E6T

Dieckmann cyclase, NcmC, bound to cerulenin

Summary for 6E6T

• Entry DOI: 10.2210/pdb6e6t/pdb
• Descriptor: NcmC, SULFATE ION, (4S,5R)-4,5-dihydroxy-5-[(3E,6E)-octa-3,6-dien-1-yl]pyrrolidin-2-one, ... (4 entities in total)
• Functional Keywords: dieckmann cyclase, off-loading, dieckmann condensation, lyase-antibiotic complex, lyase/antibiotic
• Biological source: Saccharothrix syringae
• Total number of polymer chains: 2
• Total formula weight: 58271.46

Authors

Cogan, D.P.,Nair, S.K. (deposition date: 2018-07-25, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Cogan, D.P.,Ly, J.,Nair, S.K.; Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation.; Acs Chem.Biol., 2020; PubMed: 33017142; DOI: 10.1021/acschembio.0c00579

Experimental method

X-RAY DIFFRACTION (1.6 Å)