6E3W
Structure of human DNA polymerase beta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
Summary for 6E3W
Entry DOI | 10.2210/pdb6e3w/pdb |
Related | 4XK3 4XK5 4XK7 |
Descriptor | DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*(A38) P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (8 entities in total) |
Functional Keywords | dna polymerase, transferase-dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48307.67 |
Authors | Koag, M.-C.,Lee, S. (deposition date: 2018-07-15, release date: 2019-04-03, Last modification date: 2023-10-11) |
Primary citation | Koag, M.C.,Jung, H.,Lee, S. Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc., 141:4584-4596, 2019 Cited by PubMed: 30817143DOI: 10.1021/jacs.8b08551 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
Download full validation report