6E27
The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites
Summary for 6E27
| Entry DOI | 10.2210/pdb6e27/pdb |
| Descriptor | Caspase recruitment domain-containing protein 9, ZINC ION (3 entities in total) |
| Functional Keywords | card, innate immunity, signaling protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 22446.87 |
| Authors | Holliday, M.J.,Ferrao, R.,Boenig, G.,Deuber, E.C.,Fairbrother, W.J. (deposition date: 2018-07-10, release date: 2018-09-26, Last modification date: 2024-03-13) |
| Primary citation | Holliday, M.J.,Ferrao, R.,de Leon Boenig, G.,Estevez, A.,Helgason, E.,Rohou, A.,Dueber, E.C.,Fairbrother, W.J. Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9. J. Biol. Chem., 293:16803-16817, 2018 Cited by PubMed: 30206119DOI: 10.1074/jbc.RA118.004821 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.811 Å) |
Structure validation
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