6E27

The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites

6E27 の概要

• エントリーDOI: 10.2210/pdb6e27/pdb
• 分子名称: Caspase recruitment domain-containing protein 9, ZINC ION (3 entities in total)
• 機能のキーワード: card, innate immunity, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22446.87

構造登録者

Holliday, M.J.,Ferrao, R.,Boenig, G.,Deuber, E.C.,Fairbrother, W.J. (登録日: 2018-07-10, 公開日: 2018-09-26, 最終更新日: 2024-03-13)

• 主引用文献: Holliday, M.J.,Ferrao, R.,de Leon Boenig, G.,Estevez, A.,Helgason, E.,Rohou, A.,Dueber, E.C.,Fairbrother, W.J.; Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.; J. Biol. Chem., 293:16803-16817, 2018; PubMed: 30206119; DOI: 10.1074/jbc.RA118.004821

実験手法

X-RAY DIFFRACTION (1.811 Å)