6E1V

Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 3: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine

Summary for 6E1V

Entry DOI	10.2210/pdb6e1v/pdb
Descriptor	RNA (33-MER), 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine (3 entities in total)
Functional Keywords	preq1 riboswitch, synthetic compound, complex, rna
Biological source	Caldanaerobacter subterraneus subsp. tengcongensis
Total number of polymer chains	1
Total formula weight	10478.43
Authors	Numata, T.,Connelly, C.M.,Schneekloth, J.S.,Ferre-D'Amare, A.R. (deposition date: 2018-07-10, release date: 2019-04-10, Last modification date: 2023-10-11)
Primary citation	Connelly, C.M.,Numata, T.,Boer, R.E.,Moon, M.H.,Sinniah, R.S.,Barchi, J.J.,Ferre-D'Amare, A.R.,Schneekloth Jr., J.S. Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10:1501-1501, 2019 Cited by PubMed: 30940810 DOI: 10.1038/s41467-019-09493-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.56 Å)

Structure validation