6DY0
Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) covalently bound to beta-lactam inhibitor ARN726, in presence of Triton X-100
Summary for 6DY0
| Entry DOI | 10.2210/pdb6dy0/pdb |
| Descriptor | N-acylethanolamine acid amidase alpha-subunit, N-acylethanolamine acid amidase beta-subunit, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | endocannabinoid, lipase, hydrolase |
| Biological source | Oryctolagus cuniculus (Rabbit) More |
| Total number of polymer chains | 2 |
| Total formula weight | 40139.94 |
| Authors | Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B. (deposition date: 2018-07-01, release date: 2018-09-26, Last modification date: 2023-10-11) |
| Primary citation | Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B. Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proc. Natl. Acad. Sci. U.S.A., 115:E10032-E10040, 2018 Cited by PubMed: 30301806DOI: 10.1073/pnas.1811759115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.014 Å) |
Structure validation
Download full validation report
