6DXZ

Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100

6DXZ の概要

• エントリーDOI: 10.2210/pdb6dxz/pdb
• 分子名称: N-acylethanolamine acid amidase alpha-subunit, N-acylethanolamine acid amidase beta-subunit, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: endocannabinoid, lipase, hydrolase
• 由来する生物種: Oryctolagus cuniculus (Rabbit); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 40515.62

構造登録者

Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B. (登録日: 2018-07-01, 公開日: 2018-09-26, 最終更新日: 2023-10-11)

• 主引用文献: Gorelik, A.,Gebai, A.,Illes, K.,Piomelli, D.,Nagar, B.; Molecular mechanism of activation of the immunoregulatory amidase NAAA.; Proc. Natl. Acad. Sci. U.S.A., 115:E10032-E10040, 2018; PubMed: 30301806; DOI: 10.1073/pnas.1811759115

実験手法

X-RAY DIFFRACTION (2.7 Å)